ABSTRACT
This article discusses the significance of root canal disinfectants and comments on how these can be used professionally. The complex root canal system is inhabited with different microbes in periapical periodontitis. There is no particular disinfectant that alone satisfactorily fulfills the entire functions essential for irrigation. Best possible irrigation is found on the combined use of two or more disinfectant, in a particular sequence. Sodium hypochlorite is the most commonly recommended endodontic irrigant, in spite of some adverse reactions. Chlorhexidine, Iodine and Chelators are successful against several bacteria and viruses, mainly in retreatment cases. Newer root canal irrigants like MTAD [Mixture of Tetracycline, Acid and Detergent], Tetraclean, Photo-activated disinfection, Electronically Activated Water, Ozonated water and lasers have potential to maximize root canal disinfection. Currently these newer irrigants could be used as an adjunct to NaOCl, while investigators are continuously looking for the subtle ideal root canal irrigant
Subject(s)
Dental Pulp Cavity/microbiology , Dental Pulp Cavity/drug effects , Root Canal Therapy , Anti-Infective Agents , Sodium Hypochlorite , Chlorhexidine , Iodine , Chelating Agents , Doxycycline , Doxycycline/analogs & derivatives , Polysorbates , Citric Acid , Citric Acid/analogs & derivatives , Cetrimonium Compounds , PolypropylenesABSTRACT
Treatment of chronic periodontitis affected patients is based on measures for reduction/ eradication of periodontal pathogens and alteration of the systemic and local host susceptibility. This study aimed to evaluation the effects of topical application of Atridox [Doxycycline gel] in management of chronic periodontitis. This study was carried out on 15 patients [aged 25-55] with chronic periodontitis. They were received scaling and root planning [SRP] alone in one side and SRP plus Atridox [Doxycycline gel] in other side. Each individual was subjected to the following measurements [1] Evaluation of the clinical parameters pre and post treatment to detect the outcome of the treatment modality and [2] Dental plaque samples initially and at 3, 6, 9 and 12 months were obtained for microbiological evaluation. [I] Atridox [Doxycycline gel] delivered locally into periodontal diseased sites reduced all subgingival bacteria and [2] Both treatment and modality led to a highly statistically significant reduction in microbiological counts as well as clinical parameters applied. No clinical relevant side effects were observed